Christina Applegate Talks Daughter’s Reaction To MS

Christina Applegate is opening up about how her daughter, Sadie Grace LeNoble, has handled her multiple sclerosis and the emotional hurdles it came with.

“In my situation, Sadie only knew me as healthy and a runner and a Pelotoner and a dancer — and she only knew that,” she said. “She was like stoic about it,” Applegate recalled during a Wednesday episode of her podcast “MeSsy,” which she hosts with actor Jamie-Lynn Sigler.

The “Dead To Me” star, who was diagnosed with MS in 2021, shared that her daughter initially showed a “stoic” response to the life-change news.

Applegate also described the emotional toll her condition has taken on their day-to-day relationship.

“I see her look at me when I’m in bed,” she confessed. “And can’t quite move or, I want to go say goodnight to her in her room, but I can’t quite get down the hallway for whatever reason, my legs aren’t working that day.”

The “Married… with Children” star said that her daughter’s journey has involved adjusting to a “new normal” — one where the mother she once knew is no longer the same. Applegate admitted she can sense how much it’s affected her child.

“The more she’s gotten older now, I think the more it’s hurting her,” Applegate said.

“Three years since I was diagnosed, I’ve been in the hospital upwards of 30 times from throwing up and diarrhea and pain that is unimaginable,” she revealed. “They’ve done every test known to man on me, put so much radiation into my body from CT scans to everything else.”